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Isotretinoin is considered a gold standard in treating severe cases of acne. It brings lots of benefits but on the other hand can cause series of undesirable side-effects. We present 2 cases of patients suffering from acne fulminans in the course of treatment with oral isotretinoin. Acne fulminans is a very severe systemic disease and its course is difficult to foresee. The most important is rapid diagnosis and implementation of treatment. Systemic corticosteroids combine

Acne fulminans in the course of oral isotretinoin treatment. Presentation of cases