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Urine dipstick testing for ketones is widely used when diabetic ketoacidosis (DKA) is suspected in patients with hyperglycaemia. If urinary ketones are positive, patients are referred for further management--often inappropriately, as the test is a poor surrogate for plasma ketones. Plasma beta-hydroxybutyrate (β-OHB) levels&gt;3 mmol/L are diagnostic of DKA, while levels&lt;1 mmol/L are insignificant.

The role of point-of-care blood testing for ketones in the diagnosis of diabetic ketoacidosis