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ICM0301A (1), B (2) and their congeners (3 approximately 8) were isolated from a culture broth of Aspergillus sp. F-1491 as new angiogenesis inhibitors. Their structures were elucidated by spectroscopic analyses. ICM0301A and B have a substituted decalin skeleton containing two oxirane rings.

ICM0301s, New Angiogenesis Inhibitors from Aspergillus sp. F-1491: II. Physico-chemical Properities and Structure Elucidation