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A new compound, IB-00208, has been isolated from the fermentation broth of an actinomycete isolated from a marine environment. The strain was identified as Actinomadura sp. by its chemical and phylogenetic characteristics. The compound shows cytotoxic activity on tumor cell lines and bactericidal activity against gram-positive bacteria.

journal of antibiotics

IB-00208, a New Cytotoxic Polycyclic Xanthone Produced by a Marine-derived Actinomadura. I. Isolation of the Strain, Taxonomy and Biological Activites.