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In the course of our continuing search for new bioactive fungal products we disclosed recently the strain Agrocybe sp. HKI 0259 as the producer of a new antibacterial compound. The strain Agrocybe sp. HKI 0259 was isolated from the basidiospores of Agrocybe spec. (Pediadeae) in a deciduous forest with Lithocarpus pachycarpa, Archidendron clypearia, Eurya nidita and Elaeocarpus varunua in Bach Ma (Vietnam). The pileus of the basidiomata is 4.4cm in diameter, beige-brown, in the middle brown and lamellae are greyish to brownish with slightly violet colour, in the middle 5mm broad. On the edge of the lamellae cheilocystidia are located. The stipe is 8.5cm long, white, hollow, fragile, without veil and on the base with rhizomorphs.

Agrocybolacton, a New Bioactvi Metabolite from Agrocybe sp. HKI0259.