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Spectroscopic data define the structures of the flagranones A (2), B (3) and C (4) from the nematode-trapping fungus Duddingtonia flagrans. These antibiotics are structurally related to the farnesylated cyclohexenoxides of the oligosporon group recently isolated from the nematode-trapping fungus Arthrobotrys oligospora, and show similar antimicrobial activity.

Structures of Flagranones A, B and C, Cyclohexenoxide Antibiotics from the Nematode-trapping Fungus Duddingtonia flagrans.