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Glisoprenins C, D, and E, new glisoprenin derivatives, were isolated together with glisoprenin A from submerged cultures of the deuteromycete Gliocladium roseum HA190-95. All glisoprenins inhibited appressorium formation in Magnaporthe grisea on inductive (hydrophobic) surfaces. The compounds exhibited moderate cytotoxic, but no antifungal, antibacterial or phytotoxic activities.

journal of antibiotics

Glisoprenins C, D and E, New Inhibitors of Appressorium Formation in Magnaporthe grisea, from Cultures of Gliocladium roseum. 1. Production and Biological Activities.