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Since the discovery ofcarbomycin^ in 1952 more than seventy 16-membered macrolide antibiotics have been isolated and characterized2*. The macrolides consist of an aglycon skeleton to which basic aminoor neutral sugars are attached. Three different carbon skeletons, which showcharacteristic ultraviolet absorption spectra have been characterized. They are represented by leucomycin, tylosine and aldgamycin. So far, five different types of chromophores, a,/?,y,(5-unsaturated alcohol (232nm,

A New 16-Membered Chalcomycin Type Macrolide Antibiotic, 250-144C.