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shown in Fig. 1). In this communication, we describe fermentation, isolation, structure elucidation and antitumor activities of F390B, C and nidulalin A. Culture, AJ117292, was isolated from a soil sample collected at KanagawaPrefecture, Japan and the fungus, AJ117291 was isolated from a soil sample collected at Ehime Prefecture, Japan. Both of the strains were identified as Penicillium sp. by morphological characteristics, and AJ117292 was deposited at the National

F390B and C, New Antitumor Dihydroxanthone Derivatives Isolated from Penicillium sp.