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Myxococcus flavescens AJ12298 was found to produce the complex of macrocyclic antibiotics named megovalicins. The physico-chemical studies revealed that megovalicins C and B were identical to myxovirescin A1 and antibiotic M-230B, respectively, and that megovalicins A, D, G and H were closely related new antibiotics.

Novel macrocyclic antibiotics: Megovalicins A, B, C, D, G and H. II. Isolation and chemical structures of megovalicins.