English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Saccharomyces cerevisiae in a medium without supplement of ergosterol. We now have isolated a new sterol from a culture broth of a Penicillium and found that this new sterol, named paxisterol, has analgesic activity in the mouse AcOH writhing assay1}. In contrast to corticosteroid, paxisterol does not have antiinflammatory activity. These results suggest that paxisterol is a new class of analgesic sterol and is of interest to use in modifying pain which has been difficult to relieve. Wehave isolated a new fungal steroid from a fermentation broth of a Penicillium KAC1843. Strain KAC1843 was isolated from fallen leaves of a Saghalien spruce growing in OnumaPark, Hokkaido, Japan, and has been identified as Penicillium paxilli. Fermentation was carried out at 25°C for 5 days under aeration and agitation in a 30-liter jar fermentor containing 1 8 liters of a culture medium consisting of sucrose 5%, corn steep liquor 2%, KH2PO4 0.05%, MgSO4-7H2O 0.05%, CaCO3 0.5%, pH 7.0.

Paxisterol, a new analgesic sterol without anti-inflammation activity from Penicillium.