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7 beta-[2-(2-Aminooxazol-4-yl)-2-Z-methoximinoacetamido]-3-cep hem -4-carboxylic acids 12 and 13 were synthesized. The microbiological activity of 12 and 13 as well as the beta-lactamase stability of 12 were discussed. Both 12 and 13 were quite active against a wide variety of microorganisms although usually less active than cefotaxime.

The synthesis and biological evaluation of 7.BETA.-(2-(2-aminooxazol-4-yl)-2-Z-methoximinoacetamido)cephalosporin antibiotics.