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phores with ruminant growth promoting properties, we have previously reportcd the structure of antibiotic M1396032), the行rst tetronic acidcontainillg polyether. We now wish to describe antibiotic M144255, a monocarboxylic acid type ionophore from a strain of Streptomyces griseus. It has a high affinity fbr divalent cations especially zinc, for which reason it was given the trivial name, zincophorin. The molecular structure and absolute stereochemistry(Fig.1)were determined by X-ray analysis on the mixed zincInagnesium salt(see below)1). Although zinco.

journal of antibiotics

The structure and absolute stereochemistry of zincophorin (antibiotic M144255): A monobasic carboxylic acid ionophore having a remarkable specificity for divalent cations.