English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Hygromycin was first reported in 19531,2) and several identical antibiotics such as homomycin and 1703-18B have been described.3, 4,5) Although the structure of the antibiotic was determined by chemical degradations,6,7,8) some structural aspects must still be resolved. First, neoinosamine-2 is known to be a constituent with a methylene substitution, whose location, however, has not been definitely established so far. It has been suggested that the substituent is located either on the 4, 5or the 5, 6-position by the fact that one mole of periodate was consumed by the N-acetate of methylene neoinosamine-2.9) Second, the anomeric configuration of the 6-deoxy-5-oxoarabino-hexose moiety is also unknown. To solve these problems the following experiments were undertaken employing the antibiotic St-4331 recently isolated in these laboratories from a strain of Streptomyces during the systematic screening using Mycoplasma

On the structure of hygromycin. The location of a methylene substituent and the anomeric configuration of the Arabino-hexoside moiety.