English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

We have read the article by Chao et al. with great interest. Persistent left superior vena cava (PLSVC), an important congenital anomaly that increases coronary venous pressure because of increased coronary venous volume, was found to have a prevalence of 0.29 % as in the literature. 1 It is known that increased hyperpigmentation and lesions such as ulcers in the skin develop many years after the onset of increased venous pressure in the lower extremity. 2 Although there are various pathological conditions that dilate coronary veins such as PLSVC 3 and the concept called “varicose vein of the heart” has been reported in the literature, 4 whether this chronic pressure burden on the coronary veins in humans disturbs the myocardium or has an adverse effect on its systolic and diastolic functions is yet to be demonstrated. Chronic coronary venous insufficiency is a phenomenon that has recently been experimentally described, and it shows that myocardium tissue is damaged as a result of the heart veins being exposed to chronic pressure burden 5 (Figure 1). In their study where they compared the echocardiographic results of two neonatal groups with and without PLSVC, Chao et al. reported that there was not significant difference between the two groups and that all members of the group with PLSVC were asymptomatic. 1

How Does Persistent Left Superior Vena Cava Affect Human Heart Health?