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Los implantes de titanio presentan comprobada biocompatibilidad no obstante carecen de propiedades osteoinductoras. Las estrategias actuales de modificación superficial de los implantes no resultan plenamente efectivas en casos particulares de baja calidad del hueso receptor. La presente tesis doctoral plantea una nueva estrategia basada en recubrimientos superficiales bioabsorbibles de base silicio para mejorar el éxito de dichos implantes. Para alcanzar dicho objetivo se han sintetizado vía sol-gel diversos recubrimientos a partir de los precursores de silicio trimetoximetilsilano (MTMOS), 3-glicidoxipropiltrimetoxisilano (GPTMS) y tetraetoxisilano (TEOS). Se ha realizado una detallada caracterización de los recubrimientos, especialmente en lo que a sus propiedades físicas, químicas y biológicas se refiere. Los resultados obtenidos muestran que todos los recubrimientos se encuentran bien adheridos a la superfície metálica, además, el prototipo final ha demostrado ser claramente biocompatible con los tejidos vivos sin mermar las propiedades osteoconductivas de los implantes de titanio comerciales.Titanium dental implants have proved biocompatibility, nevertheless, they lack of osteoinductive properties. The usual strategy of modifying titanium dental implants' surfaces is not fully effective in the special situations of poor bone quality. THis work focuses on a new strategy that consists on developing synthetic and biologically absorbable silica-based external coatings to improve these implants' success. In order to achieve this purpose, sol-gel technology was used to synthesize several coatings based on the precursors trimethoxymethylsilane (MTMOS), 3-glycidyloxypropylsilane (GPTMS) and tetraethoxysilane (TEOS). The coatings were thoroughly characterized, specifically focusing on their physical and  chemical properties as well as on their biological performance. Resukts show taht all the synthesized coatings were well adhered to the metal surface and the final prototype shows clear biocompatibility with living tissues without affecting the osteoconductive properties of the commercial titanium dental implants

Development of hybrid coatings for osseointegration improvement of metal dental implants