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[2] Alvarez, R., The Use of NBS Standard Reference Materials in Validating Trace Element Determinations in Biological Materials, in: Trace Elements in Man and AnimalsTEMA 5, Mills, C. F., Bremner, I., and Chesters, J. K., Eds., Commonwealth Agricultural Bureaux, Farnham Royal (1985) p. 655. [31 Byrne, A. R., Camara-Rica, C., Cornelis, R., de Goeij, J. J. M., Iyengar, G. V., Kirkbright, G., Knapp, G., Parr, R. M., and Stoeppler, M., Fresenius Z. Anal. Chem. 326, 723 (1987). [4] Veillon, C., Patterson, K. Y., and Reamer, D. C., Preparation of a Bovine Serum Pool to be Used for Trace Element Analysis, in: Biological Reference Materials, Wolf, W. R., Ed., John Wiley and Sons, Inc., New York (1985) p. 167. (5] Veillon, C., Lewis, S. A., Patterson, K. Y., Wolf, W. R., Harnly, J. M., Versieck, J., Vanballenberghe, L., Cornelis, R., and O'Haver, T. C., Anal. Chem. 51, 2106 (1985). [6] Andersen, J. R., Gammelgaard, B., and Reimert, S., Analyst 111, 721 (1986). [7] Versieck, J., Hoste, J., Vanballenberghe, L., De Kesel, A., and Van Renterghem, D., J. Radioanal. Nucl. Chem., in press. [81 Versieck, J., Vanballenberghe, L., de Kesel, A., Hoste, J., Wallacys, B., Vandenhaute, J., Baeck, N., Steyaert, H., Byrne, A. R., and Sunderman, F. W., Certification of a Second Generation Biological Reference Material (FreezeDried Human Serum) for Trace Element Analysis, submitted for publication.

Detecting contamination or trends in the concentrations of trace-metals in marine environments