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1 H-MRS, which is a method of measuring fat and iron deposits in the liver, has a single voxel spectroscopy imaging method called high-speed T 2 -corrected multiecho (HISTO) based on the STEAM method. If HISTO measurement accuracy is high, it will be one of the biomarkers, so the measurement accuracy was examined. We imaged a self-made phantom simulating a known amount of fat and iron deposition in the liver. A regression analysis of HISTO-measured values for hepatic fat phantom was performed. In addition, regression analysis was performed on the hepatic iron phantom for the R 2 values obtained from the T 2 values measurement and the actually measured value of the HISTO. From the regression analysis, the correlation coefficients were 0.999, 0.992 and 0.977, respectively. The measurement accuracy of HISTO is high, and the reliability of the obtained fat and iron deposit value is high.

Measurement Accuracy of Fat and Iron Deposits in the Liver Using <sup>1</sup>H-MRS (HISTO)