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The solubility of fudosteine has been determined in pure methanol, ethanol, water and in mixed solvents of methanol + water and ethanol+ water over the temperature range of (278.15 to 308.15) K at atmosphere pressure. The solubility is high in water, lower in ethanol. In the binary mixtures, the solubility of fudosteine increases with increasing concentration of water. The solubility of fudosteine increases with increasing temperature. The temperature dependence on the solubility data was well-correlated with the modified Apelblat equation, which could be used as a useful model for the purification process of fudosteine.

Solubility of Fudosteine in Some Pure and Mixed Solvents from (278.15 to 308.15) K