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Pontine micuturition center and storage center are controlled by upper brain. Pharmacological and molecular biological data indicate the distribution of muscarinic receptor subtypes in rat brain, however, the effect of central muscarinic cholinergic mechanisms on the bladder activity has not been evaluated. We investigated the diversity of effect of each subtype in rat brain.

THE EFFECTS OF THE ANTAGONISTS OF MUSCARINIC ACETYLCHOLINE RECEPTOR SUBTYPES IN RAT BRAIN ON URINARY BLADDER CONTRACTION