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A method for clinical evaluation of antimicrobial agents on complicated urinary tract infections was reported. The outlines were summarized as follows. 1) Complicated UTI with underlying diseases of the urinary tract in patients over 16 years old of both sexes is adopted as an object. 2) Pyuria over 5 cells/hpf and bacteriuria over 104 CFU/ml are considered to be necessary as a condition of patient. 3) The clinical efficacy of the drug has to be estimated after a 5 days' treatment. 4) The overal clinical efficacy has to be evaluated based on the response of pyuria and bacteriuria. Symptoms were not availed as a parameter of overall clinical efficacy because of the low frequency. 5) Method for classifying the type of infection which affects the efficacy of drugs was reported.

METHOD FOR CLINICAL EVALUATION OF ANTIMICROBIAL AGENTS ON URINARY TRACT INFECTIONS