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Dear colleagues, welcome to issue 2 of volume 16 of the journal. The feedback from our first 60-page volume, 16:1, has been very positive and really encourages us to push even further forward with page count, and even with an increase in the number of issues per year from the current quarterly appearance of the journal to a possible 6 issues per volume. This is very easy for us to say, but we will only be able to accomplish it if we keep receiving enough papers, not only just to maintain our page count, but of the requisitely high standard to satisfy the requirements of both our panel of peer reviewers, and the strict guidelines laid down by Medline, to which as you know we have applied for inclusion in the Medline indexing service. Please, therefore, consider Laser Therapy first as the forum in which you can publish your articles. The main point I should like to make in this Editorial is that all laser surgery depends for its good effects compared with conventional surgical approaches on the fact that light energy is the surgical tool being used. As I have reported before (Ohshiro T (2005): Auto-simultaneous laser treatment. Laser Therapy, 14: 11-17.), my classification of laser medical application by the effect of the intervention in tissue contains the very important subset of ‘autosimultaneous laser treatment’: basically this refers to the athermal and atraumatic photobioactivative effect in cells at the very periphery of a surgical laser impact brought about by the low photon intensities in this zone, the majority of the photon energy having been dedicated to the photosurgical effects, such as vaporization, coagulation and protein denaturation. Without the direct athermal and atraumatic photon-cell energy exchange which occurs in the outermost zone affected by the incident photons, Laser surgery would not have the excellent and interesting results that it does. A good example of this is the paper in the present issue by Doanh and Khang on the use of the CO2 laser for removal of condyloma accuminata is a very good example of the type of paper we will always be very happy to accept: at face value, it is a purely surgical paper, but as the authors point out in the Discussion section, it is the events occuring at the periphery of the destructive surgical beam which give this procedure its high success rate and less postoperative pain but with robust follow-ups and no recurrence. We at Laser Therapy will welcome all surgical laser papers for consideration, always provided there is some discussion of the importance of autosimultaneous laser treatment to the final good effect. Regarding preparing your article for submission to the journal, in my Editorial to 16:1 I outlined the necessary very comprehensive parametric-based approach in order to allow others to duplicate your study, and to satisfy the criteria demanded by the journal’s peer reviewers. I would like in this Editorial to offer some hints on the actual organization of the paper data. (The following is extracted from Calderhead RG [2003]: Preparation of a scientific paper on clinical laser research or applications: pitfalls and how to avoid them. In Laser Florence 2002, SPIE proceedings, 5287: 7) “For in vitro studies, please give details on how the cells were cultured, counted and handled. Any special processes, for example genetic splicing, polymerase chain reaction (PCR) techniques or immunohistochemical assays such as Northern or Western blotting should be given in detail, although this can be somewhat shortened if a technique used in a previously published paper is referenced. The division of the cells into different groups will usually be detailed here, including (it is hoped) one or more control groups. Details of how the cells were irradiated should then be given, and a concise description of the preparation of the cells for the final viewing techniques. In vivo studies usually proceed from the section on the laser or lasers straight to the detail of what was done to the animals or human subjects to help answer the originally-stated problem. For animals, the way the animals were handled and irradiated should be described in enough detail to allow others to repeat your experiment or treatment technique exactly. A diagramme showing the irradiated point or points is helpful. The treatment regimen should be described, and details of how the control animals were handled is PHOTHERAPY IS THE BASIS OF THE GOOD RESULTS ASSOCIATED WITH LASER SURGERY