Open AccessShort Laminin Peptide for Improved Neural Stem Cell Growth
Author(s) -
Li Xiaowei,
Liu Xiaoyan,
Josey Benjamin,
Chou C. James,
Tan Yu,
Zhang Ning,
Wen Xuejun
Publication year - 2014
Publication title -
stem cells translational medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.781
H-Index - 71
eISSN - 2157-6580
pISSN - 2157-6564
DOI - 10.5966/sctm.2013-0015
Subject(s) - laminin , neural stem cell , extracellular matrix , peptide , self healing hydrogels , microbiology and biotechnology , progenitor cell , biology , stem cell , in vitro , biochemistry , chemistry , organic chemistry
The authors developed a novel peptide sequence with only 12 amino acids based on the Ile‐Lys‐Val‐Ala‐Val sequence. This novel short peptide shows great promise in artificial niche development for supporting human neural stem/progenitor cell culture in vitro and in vivo and for promoting human neural stem/progenitor cell transplantation in future clinical therapy.