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Fibromyalgia (FM) is a disease of uncertain cause that is associated with chronic widespread pain and tenderness. Because the cause of FM is unclear, there is currently no curative treatment. Guidelines recommend pharmacotherapy such as pregabalin, duloxetine, amitriptyline and milnacipran hydrochloride and non-pharamacotherapy such as aerobic strengthening exercise, resistance exercise, water exercise and recognitive behavioral therapy as evidence-based therapies. However, some patients remain unable to manage their symptoms with these therapies and seek other effective treatments. Such treatments include nerve block therapy and trigger point injection (TPI) therapy. TPI is not strictly defined as nerve block therapy, but it is sometimes included in the nerve block therapy group. To date, no randomized controlled trials have been conducted to evaluate nerve block therapy for fibromyalgia alone., although many case reports have been published in Japanese. In this mini-review, we summarize and review nerve block therapy and trigger point injection therapy in English.

Consideration of the Efficacy of Nerve Block Therapy and Trigger Point Injection (Tender Point Injection) Therapy in Fibromyalgia