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Biokinetic model is a mathematical model which desc ribes the behavior of the Y in human body during the treatment of neuroendocr ine tumours. This paper presents calculation of absorbed doses in human org ans in biokinetic model Y for DOTATOC therapy. For this purpose, the human body i s represented by five compartments: blood, kidneys, urinary bladder, tumo r and liver. The input file was developed and designed to calculate absorbed doses in human organs, when compartments, as kidneys, liver and tumour, are sou rces of Y. For this purpose, computer software MCNP5/X was used. To solve the sy stem of equations obtained from the model, one data must be taken from the measurem ents of Y in blood or urine. Results obtained, showed that highest absorbed dose is in tumour, compared to other organs in human body.

Biokinetic and dosimetry of 90y-dotatoc therapy for neuroendocrine tumours