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Artículo de publicación ISIGlycolipids are biomolecules composed of a lipid chain (lipophilic) and a monosaccharideor oligosaccharide as hydrophilic group. Their chemical structure and biological role make themundoubtedly good candidates for a large and continuously growing number of biotechnologicalapplications. Mannose is a carbohydrate present on membrane glycolipids of a wide number ofpathogenic microorganisms (bacteria, fungi, protozoa, and viruses) and specifically recognizedby several lectins. We synthesized a mannose derivative linked through a short methylene chainto a pyrene moiety which behaves as a surfactant, able to aggregate, and retains the photophysicalproperties of pyrene: showing comparable absorption and emission spectra, having lowerfluorescence quantum yield and the ability to form excimer, and finally the ability to produceO2(1Δg) with high quantum yields. Thus, this novel molecule would open future applications fordetection (fluorescence) or inactivation (singlet oxygen) of bacterial pathogens, viruses, tumorcells, or particular cells.Fondecyt 	1120196 114045

Synthesis, Physicochemical and Photophysical Characterization of 4-(1-Pyrenyl)-butyl-α-D-mannopyranoside