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Opitz syndrome is a congenital disorder characterized by facial anomaly (ocular hypertelorism, widow’s peak, broad nasal bridge, and strabismus), laryngotracheal and esophageal defects, genitourinary abnormalities (hypospadias, cryptorchidism, and hypoplastic / bifid scrotum), cleft lip and palate and mental retardation. This paper reports a female patient with mandibular prognathism with Opitz syndrome treated by orthodontic treatment, orthognathic surgery and glossectomy. The case was referred to our hospital at the age of 8 years with mixed dentition for the correction of anterior crossbite. A lingual arch and a face mask were used to improve the crossbite in the right anterior teeth and mandibular prognathism. At the age of 14 years after observing growth, mandibular prognathism became prominent and surgical orthodontic treatment was commenced. Orthognathic surgery was performed at the age of 15 years using Le Fort I and sagittal split ramus osteotomies. After surgery, her occlusion was unstable due to a large tongue and a glossectomy was performed at the age of 16. After post-surgical orthodontic treatment, the occlusion was good and stable.

Opitz Syndrome: Report of a Case Treated by Orthodontic Treatment, Orthognathic Surgery and Glossectomy