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Tuberculosis constitutes a serious public health problem because it has multi-resistant forms that require treatment that is both difficult and extensive. There is a need to develop new antimycobacterial compounds, and plants represent a source of therapeutic resources. This study analyzed antimycobacterial action in eight extracts from plants found in the Brazilian Cerrado. The results showed significant inhibitory concentrations in relation to Mycobacterium tuberculosis , especially from the extracts of Apuleia molaris and Ouratea spectabilis , both of which presented reduced cytotoxic effects. Fractionation revealed a hexane fraction of A. molaris with significant and promising activity regarding future in vivo assays.

Plants from the Brazilian Cerrado with antimycobacterial effect