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Seborrheic keratosis-like melanomas (SK-like melanomas) are difficult to diagnose and easily overlooked, especially among elderly patients with multiple clinically typical SKs which are usually not dermoscopically assessed and are removed with destructive measures without histopathological confirmation [1]. Therefore, systematic dermoscopic evaluation of all SKlike lesions should be made in order to avoid misdiagnoses, delayed treatment, and medicolegal consequences. The term SK-like melanoma refers to melanoma that clinically and/or dermoscopically looks like SK, even if it is verrucous on histopathology report [1]. Comedo-like openings are predominantly found in SK, less frequently in Unna nevi, and very rarely in malignant melanoma, and they histopathologically correlate with keratin plugs within dilated follicular openings [1].

Melanoma With Comedo-Like Openings: A Rare Dermoscopic Finding