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In 2013, ex vivo derm dotting was published as a technique to mark a dermoscopically interesting area by dotting it with nail polish after fixation of the specimen [1]. Although interesting, this technique may have its disadvantages. First, the pathologist needs to know dermoscopy. Second, we already have shown that ex vivo and in vivo dermoscopic images display different features: some structures and colors are less clear or even lost, while others become more prominent [2]. This may lead to different areas of interest in vivo and ex vivo. Moreover, pathologists have been using the technique for only a few years, and they are still developing criteria for it.

In Vivo Derm Dotting: An Easy and Inexpensive Way for Clinicopathological Correlation