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Addicted patients present difficulties for pain management because they have another problem besides their pain. Adding adjuvants to opioid pumps to intensify quality, control other problems, lengthen analgesia, and reduce side effects has been considered in the field.

anesthesiology and pain medicine

Comparison the efficacy of adding clonidine, chloropromazine, promethazine and midazolam to morphine pumps in postoperative pain control of addicted patients