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Objective: Major setbacks with the use of stents, which are widely used in the treatment of coronary artery disease, are development of acute thrombosis during early term and restenosis during the long term. No procedures have been able to completely prevent formation of early stent thrombosis (ST) and in-stent restenosis (ISR) up to now. The aim of the present study was to investigate the impact of intravascular ultrasonography (IVUS) guidance on angiographic outcomes of drug eluting stent (DES) implantation. Methods: In this study, we included 23 patients who received DES with the guidance of IVUS and 23 patients receiving the DES without IVUS. The patients were scrutinized for their sixth month control angiographies. The angiographic results were compared between the groups. Results: The basic angiographic and clinical features were similar between the groups (p>0.05). The minimal luminal diameter after the percutaneous intervention was higher in Group I than Group 2 (3.2±0.3. 2.9±0.4, p=0.03). Acute ST, late lumen loss and stent restenosis rates were comparable between the groups (p>0.05). On the other hand, among the patients that did not receive IVUS three patients were presented with stent restenosis (SR) and one patient developed acute ST. Conclusion: The present results indicate that the use of IVUS for the implantation of DES can increase the success rate of the intervention. Consequently, IVUS can be considered as a complementary method during DES implantation. J Clin Exp Invest 2013; 4 (1): 84-89 OZET

The effect of intravascular ultrasound usage for the implantation of drug-eluting stent on the rate of acute thrombosis and restenosis