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Epithelial myoepithelial carcinoma (EMC) is a relatively rare, low-grade malignant tumor of the salivary gland. We report our experience with the guided nerve regeneration of the lingual nerve using a nerve guide tube (Polyglycolic acid collagen tube: PGA-C tube) after resection of an EMC that developed in the submandibular gland. The patient was a 48-year-old woman who noticed swelling in the left mandibular region. She was given a diagnosis of a tumor of the left submandibular gland on computed tomography and magnetic resonance imaging, and we performed an excisional biopsy of the region including the left submandibular gland. Pathologically, EMC was diagnosed. Accordingly, we performed extended tumor resection, including partial resection of the lingual nerve. Lingual nerve regeneration was performed on the lingual nerve deficit measuring approximately 30 mm using a PGA-C tube. The patient began to recover the tactile perception approximately 3 months postoperatively and the ability to distinguish between sweet and salty tastes approximately 1 year postoperatively. At 2 years postoperatively, she is able to distinguish sour tastes and there has been no local recurrence. Induced nerve regeneration is effective for reconstructing sensory nerves resected during surgery for malignant tumors.

神経再生誘導チューブを用いて舌神経の再生誘導術を行った顎下腺上皮筋上皮癌の1例