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Dermoid cyst and epidermoid cyst usually appear as midline swellings in the floor of the mouth. We report a rare case of epidermoid cyst that arose laterally in the root of the tongue. A 4-year-old girl with asymptomatic swelling on the left lateral aspect of the tongue was referred to our hospital. MR imaging showed a clearly defined cystic lesion. The lesion was extirpated with the patient under general anesthesia. Serous fluid and a white caseous substance were contained in the cystic lesion. Histological examination revealed a lining of squamous epithelium with mucous cells and keratin filling the lumen. A histological diagnosis of epidermoid cyst was made. The postoperative course was good, without any complications. There have been only 14 reports of dermoid or epidermoid cysts of the tongue in the English and Japanese literature. Only 4 of these cases arose in the lateral aspect of the tongue. The literature is reviewed, and possible origins of this lesion are discussed.

A case of epidermoid cyst arising laterally in the root of the tongue