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Angioneurotic edema is subcutaneous or mucosal swelling resulting from increased vascular permeability, which can be produced by a variety of conditions. There are two forms of angioneurotic edema: hereditary and non-hereditary. Deficiency of C 1 esterase inhibitor (C 1 INH) function is known to be associated with hereditary angioneurotic edema. Non-hereditary angioneurotic edema associated with deficiency of C 1 INH function is rare. We report a case of non-hereditary angioneurotic edema with facial edema triggered by odontogenic inflammation. The patient was a 58-year-old woman who was referred to our clinic because of facial swelling after pulpectomy of the right lower incisors. Marked edema was present in her face, lips, cheeks, and soft palate. Laboratory examination revealed a deficiency of C 1 INH. Because no member of her family had episodes of facial swelling or deficiency of C 1 INH, the diagnosis was non-hereditary angioneurotic edema with deficiency of C 1 INH. We describe the clinical course of the patient and the mechanism of angioneurotic edema.

A case of angioneurotic edema with C1 esterase inhibitor deficiency and repeated facial edema triggered by odontogenic inflammation