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Congenital insensitivity to pain with anhydrosis is very rare. We describe a case of congenital insensitivity to pain with anhydrosis, associated with unusual healing of a buccal ulcer, which occurred in a patient with no teeth. The patient presented with swelling of the left cheek. An ulcer with induration was found on the left buccal mucosa. The pathological diagnosis was fibromatosis. Because of recurrent swelling, we extirpated the buccal ulcer and the mass behind it. Only 3 days after operation, we found a pedicle mass at, the same location. The secondary lesion was extirpated, and pathological examination showd fibrous tissue overgrowth. Altough the wound opened after operation, it healed completely 15 months later.

A case of congenital insensitivity to pain with anhydrosis associated with unusual healing of a buccal ulcer.