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Two cases of gas gangrene in the maxillofacial region and neck that developed after odontogenic infection are reported. Case 1, a 35-year-old man, developed gas gangrene after removal of the mandibular right third molar. In case 2, a 61-year-old man, gas gangrene occurred after apical periodontitis of the mandibular right second premolar. Both cases were treated by digitally opening the site where computed tomography (CT) revealed extension of gas bubbles early after the onset of symptoms and surgical debridement with antibiotics. CT was useful in monitoring the location of gas bubbles to permit opening of the progressive large focus in multiple spaces of maxillofacial region and neck. Digital preparation of the fascia was useful for opening the focus in the early stage of the disease.

Two cases of gas gangrene in the maxillofacial region and neck induced by odontogenic infection.