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In this chapter, we will review cognitive issues faced by individuals living with neurofibromatosis. The chapter will discuss the complicated and sometimes inconsistent cognitive issues and adaptive functioning struggles associated with NF1, NF2, and schwannomatosis. We will review neurocognitive outcomes associated with each of these conditions across the lifespan while focusing on NF1. Specific neurocognitive domains we will review include: intellect, memory, language, nonverbal skills, attention, and executive functions. We will discuss the heterogeneity of the cognitive phenotype for each of these conditions. We will include how associated medical complications such as brain tumor, seizures, and hearing loss can impact neurocognitive outcomes. The chapter will also review the functional consequence of cognitive difficulties including academic struggles, learning disabilities, and decreased quality of life that are sometimes seen in this population.

Cognitive Issues Experienced by Individuals Living with Neurofibromatosis