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Bismuth has gained attention in preclinical research because of its ability to attenuate X-rays and high biocompatibility, which make it an excellent element for use in a biomedical agent or in radiation shielding. Developments in the synthesis of elemental bismuth nanoand microparticles, their X-radiation interactions, and their biological interactions will be reviewed in this chapter. The chapter will pay special focus to emerging medical applications of elemental bismuth nanoand microparticles, including the possibility of targeted molecular X-ray imaging, photo-thermal and X-radiation dose enhancing therapies for cancer treatment, and the construction of flexible radiation shielding materials and X-ray opaque devices.

Bismuth-Based Nano- and Microparticles in X-Ray Contrast, Radiation Therapy, and Radiation Shielding Applications