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Nanotoxicology, which is related with toxic potentials of nanoparticles (NPs) and their adverse effects on living organisms and environment, is a sub-branch of toxicology discipline. Nano-toxicity of NPs depends on their doses, unique chemical, and physical properties. Nowadays, silver (Ag) NPs are used in many consumer and scientific applications such as antimicrobial and pharmaceutical applications, water purification systems, textile industry, and food packaging processes. However, the information that about their nano-toxic potentials is still not complete, and it is considered that several parameters of Ag NPs such as size, shape, surface, and stability affect the toxic potential in different ways. Nano-toxic potentials of Ag NPs were mentioned as in vivo, in vitro, and in silico the studies. In this chapter, it was evaluated the common unique properties of NPs are related with nanotoxicology such as size, surface area and modifications, shape, agglomeration status, and dose.

Assessment of Nano-toxicity and Safety Profiles of Silver Nanoparticles