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Early of the last century, it was detected that antibiotics added to the animal feeds at low doses and for a long time can improve technical performances such as average daily gain and gain to feed ratio. Since then, the antibiotics have been used worldwide as feed additives for many decades. At the end of the 20th century, the consequences of the uses of antibiotics in animal feeds as growth promotors were informed. Since then, many researches have been done to find other solutions to replace partly or fully to antibiotic as growth promoters (AGPs). Many achievements in finding alternatives to AGPs in which probiotics and direct-fed microorganism, prebiotics, organic acids and their salts, feed enzymes, bacteriophages, herbs, spices and other plant extractives (phytogenic), mineral and essential oils are included.

Potential Substitutes of Antibiotics for Swine and Poultry Production