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The prevalence of human papillomavirus (HPV) infection in males is comparable to females, although in men it is largely unknown. HPV infections may be connected with the development of carcinomas and other dermoepithelial changes such as intraepithe‐ lial neoplasia. Multidirectional studies have shown that chronic HPV infection is a necessary, though insufficient factor for the development of cervical cancer. Although men are regarded as the dominant vector of HPV transmission to their female sexual partners, they do not develop clinically significant HPV-related lesions and are usually asymptomatic during relatively short infections. Analysis of data from a multicenter, clinical preventive trial was to estimate the incidence of type-specific genital infection among men and HPV transmission dynamics. The routine clinical examination included a peniscopy and detection of HPV DNA in smears using hybrid capture and in biopsy material using PCR. It is necessary to establish prevention strategies for HPV infection in men whose female sexual partners have cervical cancer. Cervical cancer prevention strategies are likewise needed and should include the use of prophylactic HPV vaccines.

Genital Human Papillomavirus (HPV) Infections in Men as a Factor for the Development of Cervical Cancer