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Extracellular vesicles (EVs), including exosomes andmicrovesicles, carry a variety of bio-macromolecules,including mRNA, microRNA, other non-coding RNAs,proteins and lipids. EVs have emerged as a promising,minimally invasive (liquid biopsies) and novel source ofmaterial for molecular diagnostics, and may provide asurrogate to tissue biopsy-based biomarkers for a varietyof diseases. Although EVs can be easily identified andcollected from biological fluids using commercial kits,further research and proper validation is needed in orderfor them to be useful in the clinical setting. Currently,several EV-based research and diagnostic companies havedeveloped research-based kits and are in the process ofworking with clinical laboratories to develop and validateEV-based assays for a variety of diseases. The successfulclinical application of EV-based diagnostic assays willrequire close collaboration between industry, academia,regulatory agencies and access to patient samples. Weexpect that international, integrative and interdisciplinarytranslational research teams, along with the emergence ofFDA-approved platforms, will set the framework for EVbaseddiagnostics. We recognize that the EV field offersnew promise for personalized/precision medicine andtargeted treatment in a variety of diseases.A short course was held as a four-session webinar series inSeptember and October 2014, presented by pioneers andexperts in the EV domain, covering a broad range of topicsfrom an overview of the field to its applications, and thecurrent state and challenges of the commercialization ofEVs for research and an introduction to the clinic. It wasconcluded with a panel discussion on the regulatoryaspects and funding opportunities in this field. A summaryof the short course is presented as a meeting dispatch

Short Course in Extracellular Vesicles — The Transition from Tissue to Liquid Biopsies