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The relationship between the effectiveness of haemodialysis on the one hand, and the flows of blood and dialysate on the other, is guided by physical principles. These principles have been known for some time and have been widely discussed in the literature [1]. However, the fact that dialysis machines are completely automated makes it easy to neglect the underlying principles, so much so that knowledge of these may at times be lacking. There are also financial pressures that result in a desire to economise on water and dialysate concentrate, and a desire to work with as low a dialysate flow rate as possible.

The Role of the Dialysate Flow Rate in Haemodialysis