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Global human population is facing the impacts of centuries of constant changes in natural environments. Impacts in the dynamics of infectious diseases are not only expected, but can already be noticed. Vector-borne diseases are particularly susceptible to environmental changes, since their occurrence depends on the ecological balance between different species in complex transmission cycles [1-3]. Leishmaniases are among the vector-borne diseases most affected by this ecological chaos driven by human actions [4], and one of the expected impacts is the expansion of its geographical distribution [5-7].

Environmental Changes and the Geographic Spreading of American Cutaneous Leishmaniasis in Brazil