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Alzheimer’s disease (AD) is a fatal neurodegenerative disorder characterized by a progressive neuronal death and loss of cognitive functions. AD is the most common type of dementia and its incidence rise to 10% in people aged over 90 [1]. Due to Increased longevity, it has been estimated that the number of people suffering from this neurodegenerative disorder will rise from 26.6 million cases in 2006 to 106,8 million worldwide in 2050 [2].

intech ebooks

Pre-Analytical and Analytical Critical Factors Influencing the High Variability of the Concentrations Levels of Alzheimer Disease Biomarkers in Cerebral Spinal Fluid