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Regardless of species, all the living organisms have poly-saccharides called glycans in their cellular surfaces or even inside the cells. The biological roles of carbohydrates are particularly important in the assembly of complex multicellular organs, which requires interactions between cells and the surrounding matrix. All cells and numerous macromolecules in nature carry an array of covalently attached sugars (monosaccharides) or sugar chains (oligosacchar‐ ides). Because many glycans are on the outer surface of cells or secreted macromolecules, they are acting to modulate or mediate a wide variety of events in cell to cell, cell with matrix, and cell with proteins or lipids critical to the development and function of complex forms of multicellular organisms (Rademacheret al., 1988; Sharon and Lis, 1993; Varki, 1993).

Glycan Profiling of Adult T-Cell Leukemia (ATL) Cells with the High Resolution Lectin Microarrays