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The perception of light underlies the processes of cognitive brain function. However, the characterizations of the neuroadaptational processes that relates to the physical quality of light, particularly those implicated in color processing remains largely unknown. Simultaneous color contrast and color constancy have been identified as the memory processes associated with color processing [1-8]. Simultaneous color contrast is the phenomenon that surrounding colors profoundly influence perceived color [1,9]. The mechanism implicated in simultaneous color contrast has been described as wavelength-differencing, implying the ability to differ‐ entiate the dominant wavelength of the color of light [10]. Wavelength-differencing involves wavelength-encoding main effect at subcortical peaks, and energy-encoding effects at cortical peaks [11]. On the other hand, frequency-differencing refers to the ability to differentiate the dominant frequency (the inverse of wavelength) of the color of light, and involves energyencoding main effect at cortical and subcortical peaks [11, 12]. Genetic studies suggest genderrelated differences in color vision in primates. Whereas both trichromatic and dichromatic color vision occurs among female monkeys, males appear exclusively dichromatic [13]. It was proposed that, unlike humans, squirrel monkeys have only a single photopigment locus on the X chromosome [13].

A New Functional Transcranial Doppler Spectroscopy (fTCDS) Study of Cerebral Asymmetry During Neuro-Cognitive Functions in Men and Women