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Increasing evidence suggests that oxidative stress plays a role in the pathogenesis of diabe‐ tes mellitus and its complications [4]. Hyperglycemia increases oxidative stress, which con‐ tributes to the impairment of the main processes that fail during diabetes, insulin action and insulin secretion. In addition, antioxidant mechanisms are diminished in diabetic patients, which may further augment oxidative stress [5, 6]. Several studies have addressed the possi‐ ble participation of dietary antioxidants, such as vitamins, in ameliorating the diabetic state and retarding the development of diabetes complications [7, 8].

Oxidative Stress in Diabetes Mellitus and the Role Of Vitamins with Antioxidant Actions