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Migraine headaches affect approximately 13% of US population, affecting women in a 3:1 ratio and with a 60–80% familial inheritance. Migraine is a relevant social health problem; in fact it significantly restricts the social life of those who are affected. Recently, migraine headache has been suspected to be a potential risk factor for stroke, particularly in women, smokers and for those making use of oral contraception.

Atrial Septal Defect/Patent Foramen Ovale and Migraine Headache